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These rats were kept under a 12 h lightdark cycle in animal housing at the Riphah Institute of Pharmaceutical Sciences, Islamabad, with a precise environment (temperature: 25 2C and humidity: 55% 5%)

Consistent with these overall rapid reaction rates of HOCl and HOBr with thiols, we found that exposure of phagocytized bacteria to oxidants produced during neutrophil respiratory burst leads to a rapid and massive breakdown of the thiol redox homeostasis of their proteome [179]

In Zip7-knockdown THP-1 cells, phagocytosis is notably less efficient, through this deficiency can be reversed by zinc supplementation

However, glutathione operates through a completely different mechanism it's a recycler and detox cofactor rather than a direct free radical quencher